SOLENTIM
CELL METRIC SYSTEMS
BENCHTOP HIGH-RESOLUTION WHOLE WELL IMAGING
Providing dedicated, purpose-designed, high-resolution whole-well imaging for daily recording of clonal outgrowth in CLD
THE TRUSTED STANDARD FOR CLONAL ASSURANCE
The Cell Metric® instrument range are high contrast imagers designed for single cell imaging, identification and clonal outgrowth characterisation. Cell Metric systems capture and record crucial evidence, whole well image of the single cell at day 0 and daily imaging thereafter, all wrapped up in a clonality report defining best practice for Master Cell Bank production. The Cell Metric X series further simplifies clonal assurance with artificial intelligence-based Automated Evidence of Clonality (AEC).
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Clonal assurance on day 0
Cell Metric set the standard for high-contrast imaging. Cell Metric X raises the bar, delivering faster, easier clonality verification on day 0 to accelerate your path to IND submission — with zero compromise in quality.
Simplify clonal assurance with AI
With the Cell Metric X series, identify single-cell clones on day 0 with artificial intelligence-based Automated Evidence of Clonality (AEC) and move from testing to IND submission weeks faster.
Demonstrated IND success
Used by leading pharmaceutical and biopharmaceutical companies and CDMOs worldwide, Cell Metric is the leading solution for compiling evidence of clonality for Investigational New Drug (IND) submissions. Cell Metric X continues that tradition, with added automation for improved efficiency and data quality.
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The Solentim ecosystem
Workflows for IND success
Assurance of clonality
Evidence that it started as a single cell
Daily whole well imaging
Cell Metric combines high quality images with data continuity, providing daily imaging with recorded evidence of single-cell to clonal growth.
High resolution images
Cell Metric combines high quality images with data continuity, providing daily imaging with recorded evidence of single-cell to clonal growth.
FEATURES
Purpose-built for imaging assurance
Right up to the edge
Solid evidence comes from clear single cell images. Sophisticated methodologies to maintain image clarity right up to the edge.
Always in focus
To manage variation across multi-well plates, proprietary laser focussing ensures optimal focal position in each and every well.
Right up to the edge
Solid evidence comes from clear single cell images. Sophisticated methodologies to maintain image clarity right up to the edge.
Always in focus
To manage variation across multi-well plates, proprietary laser focussing ensures optimal focal position in each and every well.
Clarity in purpose
Designed specifically for the needs of assurance of clonality, Cell Metric has a highly tuned brightfield optical path that maximises the clarity of single-cell imaging for assured cell line development.
Fluorescence imaging for rare event detection
As a tool for workflow verification, Cell Metric offers the option of rapid rare-event fluorescent imaging and reporting.
Clarity in purpose
Designed specifically for the needs of assurance of clonality, Cell Metric has a highly tuned brightfield optical path that maximises the clarity of single-cell imaging for assured cell line development.
Fluorescence imaging for rare event detection
As a tool for workflow verification, Cell Metric offers the option of rapid rare-event fluorescent imaging and reporting.
Automated confluence determination
For the effective tracking of daily outgrowth, Cell Metric offers automatic measurement and reporting of confluency.
An audit of cell history
Combine data from the entire timeline into a documented clonality report.
Automated confluence determination
For the effective tracking of daily outgrowth, Cell Metric offers automatic measurement and reporting of confluency.
An audit of cell history
Combine data from the entire timeline into a documented clonality report.
SYSTEMS
Cell Metric series
The trusted standard for clonal assurance
Cell Metric® is a small benchtop high-resolution whole well imaging system developed for cell line development, outgrowth optimisation studies and cell culture processing. Available as a stand-alone single plate system, or with automated plate handling within a temperature-controlled environment from Cell Metric CLD or downstream third-party robotic integration. Cell Metric also integrates with the Solentim VIPS™ system via Data Sync system for enhanced laboratory workflows.
Cell Metric series
Cell Metric X series
Simplify clonal assurance with Artificial Intelligence
Cell Metric® X streamlines and accelerates workflows with superior image resolution, Artificial intelligence (AI) and advanced automation. The Cell Metric X portfolio includes a 10-position plate stacker, and compatibility with third party robotics. Integration with the STUDIUS™ data management platform and the entire Solentim Ecosystem automates clonality reports and streamlines decision making.
Cell Metric X series
APPLICATIONS
Cell line development
Solentim’s Cell Metric systems enhance the CLD workflow to enable successful IND submissions. Built to capture solid image-based evidence of assurance, Cell Metric provides unrivalled high clarity whole well imaging.
Single cell cloning
of hiPSCs
CLD for protein therapies
Virus manufacturing for gene therapy
High efficiency, high viability single cell cloning of hiPSCs for applications including development of disease models and supporting GMP manufacture of cell therapies
Generate stable cell lines that create producing novel recombinant proteins such as monoclonal antibodies or therapeutic proteins for rare diseases
From the selection of high producer clones to the development of stable vector producer cell lines, explore our simplified workflows for gene therapy applications
SINGLE CELL CLONING OF hiPSCs
High efficiency, high viability single cell cloning of hiPSCs for applications including development of disease models and supporting GMP manufacture of cell therapies
CLD FOR PROTEIN THERAPIES
Generate stable cell lines that create producing novel recombinant proteins such as monoclonal antibodies or therapeutic proteins for rare diseases
VIRUS MANUFACTURING FOR GENE THERAPY
From the selection of high producer clones to the development of stable vector producer cell lines, explore our simplified workflows for gene therapy applications
Vaccine production using mammalian cells
Engineered exosome producer cell lines
Cell engineering & precision gene editing
Isolate, screen and characterise attributes for clones producing novel recombinant sub-unit protein and monoclonal antibody vaccines
Establish stable producer cells for the production of engineered and cell-engineered exosomes
Optimise your drug discovery process using targeted gene editing to create stable cell lines as cellular reagents, for use in target validation, functional genomics and disease modelling
VACCINE PRODUCTION USING MAMMALIAN CELLS
Isolate, screen and characterise attributes for clones producing novel recombinant sub-unit protein and monoclonal antibody vaccines
ENGINEERED EXOSOME PRODUCER CELL LINES
Establish stable producer cells for the production of engineered and cell-engineered exosomes
CELL ENGINEERING & PRECISION GENE EDITING
Optimise your drug discovery process using targeted gene editing to create stable cell lines as cellular reagents, for use in target validation, functional genomics and disease modelling
